University of Washington
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- University of Washington
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- Higher Education, Research, Healthcare, Arts
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EP12: Kirby Winfield - Founders first VC
## Key Points ### Keywords venture capital, investment strategies, AI technology, founder insights, decision-making frameworks, early stage investing, capital allocation, startup funding, Overland AI, Kirby Winfield ### Summary In this conversation, Martin Tobias interviews Kirby Winfield, a seasoned venture capitalist and founder, discussing his journey in venture capital, particularly focusing on his investment in Overland AI. Kirby shares insights into his decision-making frameworks, the importance of founder evaluation, and the evolution of his investment strategies over the years. He emphasizes the need for confidence in capital allocation and highlights common pitfalls that investors face in early-stage ventures. The discussion culminates…
Elon Musk's Starlink swagger, SpaceX vs. the cloud giants, and Seattle’s tech universe revisited
This week: SpaceX reports its first quarter as a public company, and Elon Musk says Starlink could deliver a majority of the world's internet within a decade, leveraging production facilities in Redmond. Musk also explains the company's data center ambitions, calling terrestrial infrastructure a trivial problem next to reusable rockets. Plus: we bring two Washington tech universe posters into the studio, 17 years apart. The 2009 original turns up gems including Boeing's unlikely connection to Classmates.com, a 1990s forerunner to Facebook. The 2009 poster also brings back memories of Teledesic, the Craig McCaw venture backed by Bill Gates that tried…
Mike Kropp - Founder & CEO of Iridius
Mike Kropp is the Founder and CEO of Iridius, a Seattle-based company building compliance-ready AI infrastructure for highly regulated industries like pharma and biotech. A technology executive with over 25 years of leading engineering teams at Microsoft and AWS, Mike has played a crucial role in developing innovative products and expanding their global business adoption. Mike uses a collaborative, working backward approach to deliver products that help customers innovate and create high-impact solutions for their companies. See omnystudio.com/listener for privacy information.
Zuckerberg's yacht, Meta's layoffs, a robot pizza flameout, and a reality check on AI expenses
This week on the show: Mark Zuckerberg's superyacht arrives in Seattle the same day Meta discloses nearly 1,400 local layoffs, robot pizza startup Picnic flames out and sells to a mystery buyer, and corporate America confronts the rising cost of AI, including the leaderboard-gaming practice known as "tokenmaxxing." And we return to the theme of billionaire yachts for our trivia challenge. With GeekWire co-founders Todd Bishop and John Cook. See omnystudio.com/listener for privacy information.
Anthropic acquires Vercept, the AI job crisis scenario, and Microsoft's past Epstein connections
Anthropic acquired Seattle startup Vercept on Wednesday, raising familiar questions about the impact of early exits on the broader Seattle startup ecosystem, and the question of whether AI startups can compete long-term against the giants of the field. We dig into the deal, the public feud between two of the company's early investors on LinkedIn, and why one co-founder's prior departure to Meta may have been worth more than the entire acquisition. Plus, a new research paper envisions a 2028 "global intelligence crisis" driven by AI-fueled white collar job losses, and we're already seeing early signs in the news. Then…
Cleveland's Mayor, Seattle's Future: What happens when a city's economy shifts
GeekWire brought Cleveland Mayor Justin Bibb and Seattle tech veteran Charles Fitzgerald together on the phone Thursday after a guest column warning Seattle not to repeat Cleveland's past mistakes sparked a big response — including from Bibb himself. What followed was a constructive conversation about what cities should do when the economic ground shifts beneath them. Plus: a Seattle-to-Cleveland trip may be in the works. Related Links A warning to Seattle: Don’t become the next Cleveland Cleveland mayor responds to GeekWire guest column, calls Ohio city a ‘case study of what’s possible’ Mayor Bibb on LinkedIn: "For decades, national narratives…
Amazon's big bet, a 'MySpace for bots', and a conversation with AI veteran Oren Etzioni
Upcoming GeekWire Podcast Live Event: Join us from 4 p.m. to 6 p.m. Thursday, Feb 12 at Fremont Brewing for a live recording of the GeekWire Podcast with Todd Bishop and John Cook. Free for Fremont Chamber members, $15 otherwise. Register here. This week on the show: Andy Jassy tells Wall Street that Amazon is planning $200 billion in capital expenses this year, mostly to build out AI infrastructure, and investors give it a thumbs down. Microsoft's financial results beat expectations but the company loses $357 billion in market value in a single day after investors learn the extent of…
Transforming Science and Technology for Humankind, Emer Dooley, CDL
The Creative Destruction Lab: Connecting Innovation with Impact In this episode, Emer Dooley, site lead for the Creative Destruction Lab (CDL) at the Foster School of Business, University of Washington, discusses the CDL's mission to commercialize deep tech startups for the benefit of humankind. She elaborates on CDL’s mentoring program, which pairs high-caliber mentors with promising startups in the fields of computational health and advanced manufacturing, to guide them through critical objectives over a nine-month period. Emer also explains the program's unique funding model, the process of selecting and nurturing startups, and CDL’s significant impact on the Seattle innovation ecosystem…
Investing in Food and Growth in Africa with Luni Libes, Founder, Africa Eats
From Tech to Bananas: A New Investment Horizon This week, Ed Barker sits down with Luni Libes, one of Seattle’s most quietly influential entrepreneurs and investors. Luni built and ran multiple software companies before launching Fledge, the accelerator network that helped more than 120 founders around the world. His current focus is Africa Eats, an investment company backing a portfolio of food-focused African businesses that are growing far faster - and surviving at rates far higher - than the typical American tech startup. Luni explains why the standard venture playbook misses the realities of most global markets and walks through…
From Google and Amazon to NewDays: Why These Tech Vets Bet on AI for Dementia
In this episode of Founded & Funded, Madrona Managing Director Tim Porter sits down with Babak Parviz and Daniel Kelly, co-founders of NewDays, a platform purpose-built for older Americans living with cognitive change to help them reclaim abilities, preserve independence, and keep being themselves. Babak and Daniel share how their experience at Amazon and Google led them to apply AI in the most human way: helping people with dementia and mild cognitive impairment (MCI) with scalable solutions. They dive into: Why we chose to build at the intersection of AI and cognitive health How to translate clinical science into accessible…
Booms, Busts, and Seattle in the AI Era, with Jeff Shulman of the UW Foster School
What does Seattle gain — and lose — in times of dramatic change? University of Washington Foster School of Business marketing professor Jeff Shulman has spent years studying that question, as host of the Seattle Growth Podcast, director of the Product Management Center, and a civic voice on issues ranging from housing affordability to the campaign to bring back the Sonics. On this episode of the GeekWire Podcast, Shulman joins us to talk about Seattle’s place in the global AI boom, why the city has struggled to produce superstar startups, what AI means for marketing and education, and how civic…
James Lazarovits - Co-Founder and CEO at Archon Biosciences
James Lazarovits is the CEO and Co-Founder of Archon Biosciences, a leader at the intersection of materials engineering and artificial intelligence. James brings over 15 years of experience building, mentoring, and investing in deep tech startups across AI, software, hardware, and robotics. Before founding Archon, James was at the forefront of AI-driven computational protein design as a post-doctoral fellow and later research faculty at the Institute for Protein Design at the University of Washington, under the direction of 2024 Nobel Laureate, David Baker. There, he contributed to pioneering methods that integrate machine learning and molecular engineering to create next-gen therapeutic…
Building Biotech in Seattle: Madrona Investor Spotlight with Joe Horsman
What happens when a scientist becomes a VC? We sat down with Madrona's Joe Horsman to find out. In this episode, Joe shares his journey from late nights in the lab to helping biotech founders bring life-changing science to market. You'll hear: Why Seattle's biotech + AI ecosystem is heating up What founders need beyond funding to commercialize world-changing science. Why weekend adventures fuel Monday creativity
Innovation in Turbulent Times: Voices from the GeekWire Awards
Recorded live at the 2025 GeekWire Awards in Seattle, this episode features industry leaders navigating a shifting tech and political landscape. Amid celebrations of AI breakthroughs, startup milestones, and community-building, guests discuss deeper concerns: capital flight, regulatory headwinds, and what the region needs to retain its innovation edge. Featured on the show: Ambika Singh, founder and CEO of Armoire (Workplace of the Year winner) Joseph Williams, Washington State Department of Commerce (Public Policy Champion for Innovation) Emer Dooley, Creative Destruction Lab, University of Washington (Geeks Give Back honoree) Laura Ruderman, CEO of the Technology Alliance Aviel Ginzburg, co-founder at Foundations…
Insights from Uncommon Thinkers: How these innovators found novel approaches in their fields
This week on the GeekWire Podcast, we sit down with some of the Seattle region’s “Uncommon Thinkers” — inventors, scientists, technologists and entrepreneurs transforming industries and driving positive change in the world. We recorded the episode on location, backstage at the GeekWire Gala, where we recognized five Uncommon Thinkers through this annual awards program, presented in partnership with Greater Seattle Partners. Speaking on the episode are: Uri Shumlak, co-founder and chief scientist at Zap Energy, a physicist leading a team in pursuit of fusion energy, taking a different approach from others in the field. Read the profile. Ingrid Swanson Pultz…
Microsoft’s startup story: A new look, with insights for today
This special edition of the GeekWire Podcast is the first in a four-episode series that we’ll be publishing in the months ahead as part of our year-long Microsoft @ 50 project, recognizing the company’s 50th anniversary in April 2025. On this episode, we’ll take a fresh look at Microsoft’s startup story with tech historian and author Margaret O’Mara of the University of Washington, author of The Code: Silicon Valley and the Remaking of America; plus highlights from a recent conversation with David Marquardt, Microsoft’s first outside investor and a longtime board member. Register here for our Microsoft @ 50 event…
Archon's Jamie Lazarovits on Unlocking the Full Power of Antibodies With AI
What does it take to move from cutting-edge academic research to launching a biotech company that could transform medicine? In this week's episode of Founded & Funded, Madrona Partner Chris Picardo sat down with Jamie Lazarovitz, CEO and co-founder of Archon Biosciences, to uncover the story behind their groundbreaking protein-based biologics and their unique Antibody Cages (AbCs). From bootstrapping deep tech investments as a student to navigating the challenges of commercializing revolutionary science, Jamie shares the pivotal moments, tough decisions, and key lessons that led to Archon's creation. This isn't just a story for biotech enthusiasts — every founder can…
Uber + Expedia? Ballmer on 60 Minutes; 1980s Silicon Valley revisited; What's next for AI
This week, we imagine the possibility of Uber buying Expedia Group, based on a report by the Financial Times this week that the ride-hailing company has considered a bid for the online travel giant. It would be notable in part because Uber CEO Dara Khosrowshahi was Expedia Group’s CEO from 2005 to 2017 and remains on the company’s board. In the second segment, we enjoy highlights from the "60 Minutes" profile of former Microsoft CEO Steve Ballmer, and a separate appearance by University of Washington historian and author Margaret O'Mara on an episode of the podcast "60 Minutes: A Second…
Perseverance Over Speed: Creating a New Category with Impinj's Chris Diorio
In this episode of Founded & Funded, Madrona Managing Director Tim Porter and Venture Partner Patrick Ennis host Chris Diorio, co-founder and CEO of Impinj, the pioneer and world leader in RFID technology. Patrick and Chris have known each other for more than 24 years — since Madrona and ARCH Venture Partners co-led Impinj's first round of financing in the summer of 2000. In this episode, these three reminisce about old times and share some fun stories while diving into what it takes to truly launch a new category — and the patience required by both entrepreneurs and investors when…
Oren Etzioni - Founder of TrueMedia.org
Dr. Oren Etzioni is the founder of TrueMedia.org, a free-use product that allows critical election audiences from around the world to quickly and effectively detect deepfakes. He was the Founding Chief Executive Officer at the Allen Institute for AI (AI2), having served as CEO from its inception in 2013 until late 2022. He is Professor Emeritus at the University of Washington where he helped to pioneer meta-search, online comparison shopping, machine reading, and open information extraction. He has also authored several award-winning technical papers, and founded and sold many companies. In addition to his role at TrueMedia.org, he is currently…
The Hidden Truth of Venture and AI with GP of Pack Ventures Ken Horenstein
In this episode of The Shift AI Podcast, host Boaz Ashkenazy, founder and CEO of Augmented AI, sits down with Ken Horenstein, the founding partner of Pack Ventures, a venture firm that supports startups emerging from the University of Washington's vibrant tech ecosystem. Ken shares his journey from growing up in Vancouver, Washington, to becoming a key player in Seattle's venture capital scene, with previous roles at Microsoft's M12 and Venture Out. Ken and Boaz delve into the art of identifying what’s truly necessary for startup success. Drawing from his experience working with highly technical research scientists, Ken offers a…
AI's transparency problem: Tech leaders advocate for new insights into training data
Artificial intelligence is a powerful technology that promises to reshape the future, but it also poses many risks. One of the most pressing issues is the lack of regulation and oversight of the data used to train AI models. A new nonprofit, the Seattle-based Transparency Coalition (transparencycoalition.ai) aims to address this issue. The co-founders of the group, veteran startup founders and technology leaders Rob Eleveld and Jai Jaisimha, join us on this episode of the GeekWire Podcast to discuss their reasons for starting the organization, and their goals to help shape emerging legislation and public policy in this area. With…
Investor Spotlight: A Conversation with Madrona's Tim Porter
Hear from Madrona Managing Director Tim Porter as he discusses his path to venture capital by way of mechanical engineering and Microsoft. He shares invaluable insights about what he looks for in a founder, the importance of customer focus, and the high priority he places on integrity. Tim also shares Madrona's core principles, his favorite books for entrepreneurs, and his personal interests outside of work, including his passion for outdoor sports and the nonprofit Global Partnerships. This chat is a must-watch for aspiring entrepreneurs looking for insights into the venture capital world or strategies to capture an investor's eye. (00:00)…
The founding of Rover and the business model behind Pioneer Square Labs, a conversation with Greg Gottesman
Send us Fan Mail In 2011, Greg Gottesman had a bad experience leaving his dog for the weekend at a local Kennel. That experience led him to pitch the idea for Rover at a Startup Weekend which he won. That led to the formation of Rover and the rest is history. In our second podcast episode, Gowri Shankar and I explore the foundation of Rover as well as the business model behind Pioneer Square Labs. Greg Gottesman is a Managing Director and Co-Founder of PSL. Prior to PSL, Greg served as one of the three initial Managing Directors of Madrona…
Incubating the Next Big Ideas | with Elizabeth Scallon (Co-Founder Find Ventures, Director HP, WeWork)
In this episode of Shift AI we feature Elizabeth Scallon, a prominent figure in the Seattle startup scene who discusses her experiences and insights on co-working, mentorship, and the future of work. Elizabeth highlights the potential of AI and co-creation in scaling and accelerating work processes. and shares her expertise on funding structures for underrepresented small businesses. In this episode of Shift AI, we cover: Elizabeth discusses her first experience working and her family’s relationship to work growing up in Bellevue Washington. Elizabeth’s background as a leader in the Seattle startup accelerator scene, as a mentor and champion for small…
People
See all 25-
Oren Etzioni Executive, Former CEO, Founder and Emeritus Professor, Former Professor, Former Leader of TrueMedia
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Avi Geiger Lecturer, Affiliate Assistant Professor, Electrical and Computer Engineering
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Babak Parviz Professor
