Mary Jesse

Founder and CEO at ACME Brains
Seattle, Washington, United States

Mary Jesse is the founder and CEO of ACME Brains, Inc., vice chairman of the board at MTI - Mobile Technologies Inc., and a strategic advisor at PlayyOn. She founded ACME Brains, which is still running. Her expertise includes human-centered AI, privacy, personal technology, and advising companies on AI strategy and innovation.

Live show: Amazon, Meta and the fight over the future of AI; Plus, is Seattle still the place to build?

This week: Amazon is blocking Meta's new Muse AI assistant from shopping on Amazon.com, saying the agent doesn't identify itself and violates the site's conditions of use. We explain why the standoff is an early sign of a much bigger fight over whether AI agents can use websites and apps on people's behalf, and why Amazon has so much riding on the answer. For the definitive word on the issue, we ask Muse what it has to say for itself, and get an impressively sophisticated and evenhanded answer. We recorded this week's show live at Daniel's Broiler in downtown Seattle…

Organizations

See all 11
  • ACME Brains Founder and CEO 2025–present · current
  • PlayyOn Strategic Advisor 2025–present · current
  • MTI - Mobile Technologies Inc. Vice Chairman of the Board 2024–present, Chairman of the Board 2023–2024, Board Member 2021–2023, Chief Executive Officer 2020–2023, Chief Operating Officer 2020 · current

Education

  • Stanford University Certificate, Artificial Intelligence and Machine Learning
  • Stanford University Certificate, Generative AI
  • Harvard University Corporate Finance Coursework
  • Santa Clara University MSEE Master of Science - MS, Electrical Engineering
  • University of Utah BSEE Bachelor of Science - BS, Electrical Engineering

Online