David Baker
David Baker is Professor and Institute Leader at the University of Washington, where he also serves as Director at the Institute for Protein Design and UW Medicine’s Institute for Protein Design. He is Co-founder and Lab Head at the University of Washington Institute for Protein Design.
Accipiter Bio raises $10.5M more to speed AI-designed multi-target protein drugs, expanding clinical pipeline
Seattle biotech Accipiter Bio raised an additional $10.5 million from existing investors to accelerate development of AI-designed multi-target protein therapeutics and expand its team and clinical pipeline. The company, now 22 people strong and partnered with Pfizer and Kite/Gilead, will use the funds to advance three to four programs—focusing mainly on immunology alongside oncology—after emerging from stealth last year with $12.7 million.
University of Washington’s CoMotion Announces 10 Startups, Eight Focused on Healthcare; CoMotion Firms Raised $1.8B
University of Washington’s CoMotion announced 10 new startups spun out with UW-licensed IP, eight focused on healthcare (diagnostics, devices, therapeutics) and two on K–12 education or climate; CoMotion-backed companies have raised $1.8 billion in five years and 310 deep-tech firms have been formed over three decades.
Seattle’s UW research, Amazon alumni and military adjacency fuel startups building high-stakes, regulation-ready AI for biotech, finance and government
A Seattle high-school intern argues that strict school AI rules illuminated why AI must be disciplined in high-stakes domains, and describes how Seattle's research institutions (notably UW and the David Baker ecosystem), Amazon alumni, and military adjacency produce founders building accountable, regulation-ready AI for biotech, finance, and government.
Anindya Roy Co-founds Lila Biologics to Advance AI-Driven Medical Therapies After Journey from Rural India to UW Lab
Anindya Roy, who moved from rural India to the U.S. in 2008 with limited resources, has co-founded Lila Biologics in 2023 to develop innovative medical therapies using AI-powered protein design. His journey from humble beginnings to a postdoctoral fellowship under Nobel laureate David Baker exemplifies determination and scientific innovation.
Seattle’s Accipiter Bio Raises $12.7M, Partners with Pfizer and Kite Pharma to Advance AI-Designed Multi-Target Protein Therapies
Seattle biotech startup Accipiter Biosciences, founded by researchers from Nobel laureate David Baker's lab, secured $12.7 million and partnerships with Pfizer and Kite Pharma to develop AI-designed multi-target proteins aiming to improve disease treatment efficacy and reduce clinical trial costs.
Lila Biologics, Nobel Laureate’s Startup, Partners with Eli Lilly to Develop AI-Based Tumor Therapies
Lila Biologics, a startup from Nobel Laureate David Baker's University of Washington lab, is collaborating with Eli Lilly to develop AI-powered tumor-targeted therapies, aiming to deliver a candidate protein for clinical trials within six months. The startup utilizes AI and machine learning platforms to create therapeutic proteins for targeted radiotherapy and long-acting injectable drugs.
GeekWire Week in Review: Bill Gates Pledges $200B, Statsig Hits $1.1B Valuation, Seattle Startups Raise Millions in May 2025
This GeekWire Week in Review highlights top tech stories including Bill Gates' $200 billion philanthropy pledge, Seattle startups raising significant capital, and the emergence of new AI-driven unicorn Statsig valued at $1.1 billion. It also covers local news like a controversial Washington EV tax and cultural moments involving Seattle figures.
Trump-Era Funding Cuts and Hiring Freeze Stall UW Protein Design Startups Led by Nobel Laureate David Baker
The University of Washington's Institute for Protein Design, led by Nobel laureate David Baker, faces a hiring freeze and funding cuts under the Trump administration, stalling its promising protein design startups and reducing opportunities for graduate students and postdocs. Despite Nobel-driven interest and advances in AI-designed proteins, budget constraints threaten future innovation and company spinoffs.
Seattle Hub for Synthetic Biology Secures $10M Grant to Advance DNA Recording Technology for Disease Research
The Seattle Hub for Synthetic Biology received a $10 million grant from the Washington Research Foundation to support training scientists and launching biotech startups developing DNA recording technology for studying diseases. This initiative, launched in January 2024, is a collaboration between the Allen Institute, the Chan Zuckerberg Initiative, and the University of Washington.
Nobel Laureate David Baker Drives Protein Design Innovation and Startup Growth at University of Washington
David Baker, Nobel Prize winner and head of the Institute for Protein Design at the University of Washington, is focused on advancing protein design research and entrepreneurship, having helped spawn over 20 startups in Seattle's biotech hub. He plans to continue accelerating scientific innovation in the field, which develops new proteins for therapeutics, vaccines, and materials.
TerraPower Isotopes’ Chris Dunckley Leads Team Extracting Ultra-Rare Actinium-225 from Cold War Waste for Cancer Therapy
Chris Dunckley, director of chemistry and engineering at TerraPower Isotopes, leads a multidisciplinary team extracting the ultra-rare radioisotope actinium-225 from Cold War nuclear waste to develop promising cancer therapies. His leadership and scientific expertise help transform radioactive weapons waste into potentially life-saving medical treatments.
Archon Biosciences Raises $20M to Develop AI-Optimized Antibody Cages for Disease Treatment
Archon Biosciences has emerged from stealth with $20 million in seed funding led by Madrona Ventures to develop Antibody Cages, computationally designed protein structures optimized with AI for treating cancer and other diseases. The technology builds on protein design research linked to a recent Nobel Prize awarded to University of Washington biochemist David Baker.
Former Amazon Exec Dave Clark Launches $100M Startup Auger; UW’s David Baker Wins Nobel, Microsoft Rebrands 343 Industries to Halo Studios
The week of Oct. 6, 2024, featured top stories including former Amazon exec Dave Clark launching a $100M supply-chain startup Auger, AWS VP of AI Matt Wood departing after 15 years, and University of Washington’s David Baker winning a Nobel Prize for protein design. Microsoft also announced rebranding of 343 Industries to Halo Studios with a new direction for the Halo franchise.
Seattle Startup Arzeda Raises $38M to Advance Protein Design for Industrial and Agricultural Applications
Seattle-based protein design startup Arzeda raised $38 million in its latest funding round, bringing total investments to $86 million to develop enzymes for industrial and agricultural uses. The company works with major partners like Unilever, BP, and Gore-Tex makers, and was the first spinout from the University of Washington's Institute for Protein Design.
Cyrus Biotechnology Launches Levitate Bio to Broaden Access to Rosetta Drug Development Software
Seattle startup Cyrus Biotechnology has spun out a new for-profit company, Levitate Bio, owned by the Rosetta Commons Foundation, to expand access to its versatile drug development software platform, Rosetta. Levitate Bio, led by CEO Sam DeLuca and executive VP Karen Khar, aims to support innovation across drug development, agriculture, synthetic biology, and manufacturing.
Vilya Secures $71 Million Series A Funding Led by NVIDIA, ARCH, Madrona, and Menlo Ventures for AI-Driven Macrocyclic Drug Development
Vilya, a biotech startup developing macrocyclic drugs using AI and machine learning, announced an expanded $71 million Series A funding round led by ARCH Venture Partners, NVIDIA's NVentures, Madrona, and Menlo Ventures. The company, a spinout from Seattle's Institute for Protein Design, aims to revolutionize drug discovery with advanced protein engineering technologies.
University of Washington’s David Baker Credits Open-Code Rosetta Commons for Protein Design Startup Success
David Baker, director of the University of Washington’s Institute for Protein Design (IPD), emphasizes open code sharing as key to the institute’s success in creating protein design startups. The IPD’s collaborative Rosetta Commons consortium has enabled widespread development of protein design tools, fostering innovation and spinouts in biotech.
University of Washington’s CoMotion Spins Out Seven New Startups Including Biotech and 3D Printing Ventures Since July 2023
Since July last year, the University of Washington's CoMotion has spun out seven new startups focused on innovations from biotech to 3D printing. These are part of over 110 active UW spinouts collectively employing 1,000+ people and raising $4.1 billion in the past five years.
AstraZeneca to Acquire UW Spinout Icosavax for Up to $1.1 Billion to Boost Respiratory Vaccine Development
AstraZeneca announced it will acquire Seattle-based biotech spinout Icosavax, founded at the University of Washington, for up to $1.1 billion to accelerate development of vaccines targeting respiratory viruses. Icosavax's shares surged over 40% after the deal, which values the company at a 43% premium and aims to advance its lead RSV and hMPV vaccine candidate.
University of Washington Launches Vilya with $50 Million to Develop Membrane-Permeable Peptide Drugs
University of Washington researchers developed custom peptides that penetrate cell membranes, enabling a new class of drugs with combined benefits of small molecules and protein therapeutics. They founded Vilya, backed by $50 million from Arch Venture Partners, to commercialize this drug platform described in Cell.
Pacific Northwest Life Sciences Update: Talus Bioscience Raises $9.75M, Kineta Merges with Yumanity, UW’s David Baker Launches Charm Therapeutics
Recent Pacific Northwest life sciences news includes Talus Bioscience raising $9.75 million, Kineta going public via merger with Yumanity, and UW's David Baker launching Charm Therapeutics. Key partnerships involve TwinStrand and Singular Genomics developing rare gene variant tests, and Umoja Biopharma partnering with TreeFrog Therapeutics for stem cell therapies.
David Baker Launches London Biotech Charm Therapeutics with $50M Series A to Advance Deep Learning Drug Discovery
David Baker, leader of the University of Washington Institute for Protein Design, co-founded London-based Charm Therapeutics, which uses deep learning to discover new small molecule therapeutics, and recently secured $50 million in Series A funding. The company's DragonFold platform predicts protein-small molecule interactions to aid drug discovery in cancer and other diseases.
Cyrus Biotechnology raises $18M and acquires Orthogonal Biologics, adding COVID-19 decoy therapeutic and deep mutational scanning platform
Seattle protein engineering company Cyrus Biotechnology raised $18 million and acquired Orthogonal Biologics, adding a deep mutational scanning platform and two protein therapeutics including a potential COVID-19 decoy. Cyrus leverages University of Washington IPD tools (Rosetta, RoseTTAfold) and has partnerships including a deal with Selecta Biosciences worth up to $1.5 billion.
Icosavax IPO: Seattle biotech raises $180M, stock jumps 200% on first trading day (ICVX)
Seattle biotech Icosavax surged more than 200% on its NASDAQ debut after raising over $180 million by pricing shares at $15; the company develops virus-like particle vaccines and recently began phase 1/2 trials for a COVID-19 vaccine supported by a $10 million Gates Foundation grant.
Icosavax files for IPO after raising $150M and advancing nanoparticle COVID-19 and RSV vaccines
Seattle-based Icosavax, a 2017 spinout from the University of Washington’s Institute for Protein Design, has filed for an IPO after raising over $150 million and advancing nanoparticle-based COVID-19 and RSV vaccine candidates into early clinical trials with support from a $10 million Gates Foundation grant.
Organizations
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Institute for Protein Design Director · current
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University of Washington Professor / Institute Leader (Institute for Protein Design) · current
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UW Institute for Protein Design Co-founder and Lab Head, Nobel Laureate · current
