David Baker
David Baker is Professor and Institute Leader at the University of Washington, where he also serves as Director at the Institute for Protein Design and UW Medicine’s Institute for Protein Design. He is Co-founder and Lab Head at the University of Washington Institute for Protein Design.
Uncommon Thinkers 2025: Solar spacecraft, sci-fi biology, destroying PFAS, beyond AI chatbots, and better social media
On this special episode of the GeekWire Podcast, recorded backstage at the GeekWire Gala at the Showbox Sodo, we sit down with five of the inventors, scientists, and entrepreneurs selected as the Seattle region's 2025 Uncommon Thinkers, in partnership with Greater Seattle Partners. Jeff Thornburg spent years building rocket engines for Elon Musk at SpaceX and Paul Allen at Stratolaunch. Now, as CEO of Portal Space Systems, he's moved past chemical rockets to revive a concept NASA studied decades ago but never pursued — a spacecraft powered by focused sunlight. He calls it a "steam engine for space." Read the…
James Lazarovits - Co-Founder and CEO at Archon Biosciences
James Lazarovits is the CEO and Co-Founder of Archon Biosciences, a leader at the intersection of materials engineering and artificial intelligence. James brings over 15 years of experience building, mentoring, and investing in deep tech startups across AI, software, hardware, and robotics. Before founding Archon, James was at the forefront of AI-driven computational protein design as a post-doctoral fellow and later research faculty at the Institute for Protein Design at the University of Washington, under the direction of 2024 Nobel Laureate, David Baker. There, he contributed to pioneering methods that integrate machine learning and molecular engineering to create next-gen therapeutic…
Building Biotech in Seattle: Madrona Investor Spotlight with Joe Horsman
What happens when a scientist becomes a VC? We sat down with Madrona's Joe Horsman to find out. In this episode, Joe shares his journey from late nights in the lab to helping biotech founders bring life-changing science to market. You'll hear: Why Seattle's biotech + AI ecosystem is heating up What founders need beyond funding to commercialize world-changing science. Why weekend adventures fuel Monday creativity
Insights from Uncommon Thinkers: How these innovators found novel approaches in their fields
This week on the GeekWire Podcast, we sit down with some of the Seattle region’s “Uncommon Thinkers” — inventors, scientists, technologists and entrepreneurs transforming industries and driving positive change in the world. We recorded the episode on location, backstage at the GeekWire Gala, where we recognized five Uncommon Thinkers through this annual awards program, presented in partnership with Greater Seattle Partners. Speaking on the episode are: Uri Shumlak, co-founder and chief scientist at Zap Energy, a physicist leading a team in pursuit of fusion energy, taking a different approach from others in the field. Read the profile. Ingrid Swanson Pultz…
Archon's Jamie Lazarovits on Unlocking the Full Power of Antibodies With AI
What does it take to move from cutting-edge academic research to launching a biotech company that could transform medicine? In this week's episode of Founded & Funded, Madrona Partner Chris Picardo sat down with Jamie Lazarovitz, CEO and co-founder of Archon Biosciences, to uncover the story behind their groundbreaking protein-based biologics and their unique Antibody Cages (AbCs). From bootstrapping deep tech investments as a student to navigating the challenges of commercializing revolutionary science, Jamie shares the pivotal moments, tough decisions, and key lessons that led to Archon's creation. This isn't just a story for biotech enthusiasts — every founder can…
IA40 Spotlight: A-Alpha Bio's David Younger on machine learning in biotech, building cross-functional teams
This week on Founded & Funded, Partner Chris Picardo is talking with A-Alpha Bio Co-founder and CEO David Younger for our first Intelligent Application 40 Spotlight episode of 2023. We announced the 2022 IA40 winners in October, and A-Alpha was the first biotech company to make the list, which was no surprise to us. As one of our portfolio companies, we know the work David and his team are doing at the intersections of biological and data/computer sciences will change the world — but having a group of judges agree with us makes us all the more certain. Protein interactions…
Organizations
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Institute for Protein Design Director · current
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University of Washington Professor / Institute Leader (Institute for Protein Design) · current
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UW Institute for Protein Design Co-founder and Lab Head, Nobel Laureate · current
